1. What is AgriPhage? 

  • The AgriPhage product line consists of EPA registered pesticides featuring bacteriophage technology to prevent and treat the following diseases:
    • AgriPhage Spot & Speck (EPA Reg. 67986-1)
    • AgriPhage – Tomato Canker (EPA Reg. 67986-6)
    • AgriPhage – Fire Blight (EPA Reg. 67986-8)
    • AgriPhage – Citrus Canker (EPA Reg. 67986-9)
    • AgriPhage – Nut & Stone (EPA Reg. 67986-10)

  1. What are Bacteriophages?

  • Phage can either be pronounced as “fāj”, which rhymes with cage, or “fäj”, which rhymes with dodge. The plural is phages.
  • Coined by French-Canadian scientist Félix d’Hérelle, the Greek word “bacteriophage”, also known as “phage”, means “bacteria eater”. Phages are a class of human-safe viruses that specifically target bacteria.
  • Through a process called lysis, the bacterium is injected with DNA from the bacteriophage. This DNA then hijacks the cell’s metabolic process and forces the bacterium to produce up to a hundred new phages. This process culminates in the bacterium cell wall bursting and releasing the new phages into the environment which then attack nearby bacteria. This process repeats until the specific bacterium is eliminated and the bacteriophage decomposes into the environment.

  1. How does AgriPhage work?

  • When AgriPhage is used, the plant’s surface is covered with billions of bacteriophages and the lysing process begins immediately. For specific details about the lysing process, see the description above.
  • The number of bacteriophages increase over the course of a single treatment due to the fact that they multiply up to a hundred-fold each time a bacterium is lysed. This means that the plant’s pathogenic bacteria are overwhelmed in a natural and effective way, allowing the plant to focus on fruit production.

  1. How is AgriPhage made?

  • AgriPhage was born, researched, developed, commercialized, and continues to be produced in the USA.
  • Through more than 50 years of research, trial, and discovery, the AgriPhage product line has been proven to be safe for humans, insects, bees, beneficial bacteria, and is free of bacterial or fungal contaminants.
  • Our unique, proprietary process uses aerobic fermentation in industrial fermentors which produce a highly concentrated number of bacteriophages. In fact, 1 gallon of AgriPhage contains over 94 trillion phages!


Key Highlights

  • MRL Exempt
  • 4hr REI
  • 0 day PHI
  • Certified for organic use

  1. What are the benefits of AgriPhage?

  • AgriPhage has been proven to provide better control of bacterial diseases than traditional pesticides, significantly increase crop yields (8-33% vs. grower’s standard), and decrease the number of harsh chemicals and antibiotics ending up in the soil. Unlike traditional antibiotics, bacteriophages WILL NOT harm the beneficial organisms that play an important part in the plant’s overall well-being, which leads to better plant health, higher quality fruit, and higher yields.

  1. Will it increase my yield?

  • Because AgriPhage doesn’t contain harsh chemicals and reduces bacterial infection, plants can focus their energy on fruit growth. Healthier plants make better fruit. Studies have shown yield increases of up to 33% when compared to grower’s standard chemical applications.

  1. Is it safe to spray AgriPhage?

  • Plant health and human safety are two of the most important factors here at AgriPhage. All AgriPhage products are Maximum Residue Limit (MRL) exempt, have only a 4-hour re-entry interval (REI) for farm workers, and have a pre-harvest interval (PHI) of 0 days. All products have been reviewed by the Washington State Department of Agriculture and certified for use as an organic input, have been approved by EPA through the USDA’s National Organic Program (NOP), and are labeled “FOR ORGANIC PRODUCTION”. AgriPhage DOES NOT contain any harsh chemicals and is NEVER phytotoxic.

  1. Do I need to worry about bacterial resistance?

  • No! One of the most important and unique benefits of using AgriPhage is that you don’t need to worry about bacterial resistance. AgriPhage consists of up to eight genetically distinct bacteriophages in each bottle. This “cocktail” approach makes it extremely difficult, if not impossible, for bacteria to gain resistance to AgriPhage, regardless of repeated applications. AgriPhage has been applied weekly on thousands of tomato acres, for over 17 years in Florida with no detection of resistance. However, it’s important to maintain vigilance, which is why we constantly collect and accept infected plant samples in our state-of-the-art research facility in Salt Lake City, Utah.


  1. How do I prevent bacterial infection in my field?

  • AgriPhage can be applied throughout the growing season, from seeds and starts to maturity and harvest, as a preventative treatment. There is always a variable level of pathogenic bacteria (inoculum) at any time in every orchard or field, just waiting for the optimal environmental conditions to reproduce to high levels and show disease symptoms. Treating the plants preventatively will lower the overall inoculum so that disease symptoms are suppressed when environmental conditions change.
  • While preventative treatments are important, we understand there are situations where disease may already be present and showing symptoms on plants. AgriPhage can be used to prevent the spread of bacterial disease and encourage new, clean growth.

  1. How do I apply AgriPhage?

  • Through many years of studies and trials, the optimal concentration of AgriPhage to water is 1:400 (ex. 1 quart of AgriPhage into 100 gallons of water). However, if there are no disease symptoms present, the rate can be adjusted down to a 1:800 ratio (ex. 1 pint AgriPhage into 100 gallons of water). If disease symptoms are more severe, concentration can be adjusted as high as 1:200.

  1. What is the best time to apply AgriPhage?

  • You can apply AgriPhage products at any time of day. AgriPhage is a contact killer and will begin working immediately upon contact, reproducing and increasing in numbers until there are no more host bacteria available. Because of this lysing process and quick kill, proper plant spray coverage is very important.

  1. What is the timing of sprays?

  • Timing is different in each crop sprayed:
  • Tomatoes and Peppers: Apply weekly during the season starting at transplant through harvest.
  • Citrus: Apply every 14-21 days, attempting to time applications with flushes of new, young plant growth. Keeping young flushes free of citrus canker lesions will help limit the spreading of disease throughout the tree canopy.
  • Stone Fruit: Apply beginning at shuck split and through each cover up to harvest. AgriPhage can be applied to the tree after harvest as a “clean up” treatment.
  • Apples and Pears: Apply at bloom starting at pink and at each blossom application through petal fall. Increased control of shoot blight can be achieved by extending applications of AgriPhage through to harvest.

  1. Can I mix anything with AgriPhage?

  • AgriPhage shouldn’t be mixed with copper-based treatments or other denaturizing agents, but AgriPhage can be mixed with most other treatments and fertilizers. Add AgriPhage to your tank-mix last; following the addition and dilution of all other chemicals and treatments. OmniLytics continually tests new products for compatibility. Please see our extensive compatibility list and contact us if the chemical in question is not listed. 

  1. How long can it be stored?

  • Store AgriPhage under refrigerated conditions (approximately 39.2°F (4°C)) and in a dry area. Direct sunlight and/or extreme heat may cause degradation of the product and decrease product efficacy. AgriPhage is stable for over 18 months when properly stored according to the label.

Contact the Staff at AgriPhage™ Today to Learn More About Our Product or to Place an Order!